Article
Angiotensinogen genotype predicts abnormal renal hemodynamics in young hypertensive patients.
Journal of hypertension - 1 Jul 2008
Patel Tejas V, Williams Gordon H, Fisher Naomi Deirdre L
Abstract excerpt
OBJECTIVE: In essential hypertensive patients, blunted renal plasma flow responsiveness to angiotensin II suggests a pathologic increase in angiotensin II in the kidneys. This blunting has been associated with the angiotensinogen 235TT genotype. As several measures of renal function decline with age, we sought to determine the interaction of age and genotype on this intermediate phenotype. DESIGN AND METHODS:...
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