Article
Angiotensinogen gene core promoter variants and non-modulating hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 2001
Hilgers K F, Delles C, Veelken R, Schmieder R E
Abstract excerpt
Non-modulation has been suggested as a possible intermediate phenotype defining a subgroup of genetic hypertension. The trait is characterized by an attenuated response of renal blood flow and/or aldosterone to angiotensin (Ang) II. We tested the hypothesis that functional polymorphisms of the core promoter of the angiotensinogen gene are associated with non-modulation. Fifty-six young, white, male, untreated...
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