Article
Impact of p53 status on heavy-ion radiation-induced micronuclei in circulating erythrocytes.
Mutation research - 3 Mar 2000
Chang P Y, Torous D, Lutze-Mann L, Winegar R
Abstract excerpt
Transgenic mice that differed in their p53 genetic status were exposed to an acute dose of highly charged and energetic (HZE) iron particle radiation. Micronuclei (MN) in two distinct populations of circulating peripheral blood erythrocytes, the immature reticulocytes (RETs) and the mature normochromatic erythrocytes (NCEs), were measured using a simple and efficient flow cytometric procedure. Our results show...
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