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Chromosomes Lacking Telomeres are Present in the Progeny of Human Lymphocytes Exposed to Heavy Ions

1 Jan 2006

Abstract excerpt

High-charge and energy (HZE) nuclei represent one of the main health risks for human space exploration, yet little is known about the mechanisms responsible for the high biological effectiveness of these particles. We have used in situ hybridization probes for cross-species multicolor banding (RxFISH) in combination with telomere detection to compare yields of different types of chromosomal aberrations in the...

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PMID: 16392962
DOI: 10.1667/rr3477.1

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