Article
Chromosomal instability induced by heavy ion irradiation.
International journal of radiation biology - 1 Dec 2000
Limoli C L, Ponnaiya B, Corcoran J J, Giedzinski E, Morgan W F
Abstract excerpt
PURPOSE: To establish the dose-response relationship for the induction of chromosomal instability in GM10115 cells exposed to high-energy iron ions (1 GeV/nucleon, mean LET 146 keV/microm) and gold ions (11 GeV/nucleon, mean LET 1450 keV/microm). Past work has established that sparsely ionizing X-rays can induce a long-lived destabilization of chromosomes in a dose-dependent manner at an incidence of...
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