Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic link between co-suppression and RNA interference in C. elegans.

Nature - 16 Mar 2000

Ketting R F, Plasterk R H

Abstract excerpt

Originally discovered in plants, the phenomenon of co-suppression by transgenic DNA has since been observed in many organisms from fungi to animals: introduction of transgenic copies of a gene results in reduced expression of the transgene as well as the endogenous gene. The effect depends on sequence identity between transgene and endogenous gene. Some cases of co-suppression resemble RNA interference (the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caenorhabditis elegans Proteins
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Genes, Helminth

Share to Helminth Proteins

Share to RNA, Double-Stranded

Share to RNA, Helminth

Source

Identifiers

PMID: 10749214
DOI: 10.1038/35005113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic link between co-suppression and RNA interference in C. elegans.PMID 10749214Read ↗

RNA helicase MUT-14-dependent gene silencing triggered in C. elegans by short antisense RNAs.Semantic proximity Read ↗

RNAi (Nematodes: Caenorhabditis elegans).Semantic proximity Read ↗

Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi.Semantic proximity Read ↗

Uncover genetic interactions in Caenorhabditis elegans by RNA interference.Semantic proximity Read ↗

Genetic enhancers.Semantic proximity Read ↗

Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution.Semantic proximity Read ↗

The rde-1 gene, RNA interference, and transposon silencing in C. elegans.Semantic proximity Read ↗

Crosstalk between and developmental dynamics of <i>C. elegans</i> Argonaute proteinsSemantic proximity Read ↗

Co-option of the piRNA pathway for germline-specific alternative splicing of C. elegans TOR.Semantic proximity Read ↗

Transposon Regulation in the <i>Caenorhabditis elegans</i> Germline and SomaSemantic proximity Read ↗

Towards full employment: using RNAi to find roles for the redundant.Semantic proximity Read ↗

Divergent C. elegans toxin alleles are suppressed by distinct mechanisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.