Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-jun

1 May 2000

Abstract excerpt

Helicobacter pylori is an etiological agent in the development of mucosa-associated lymphoid tissue lymphoma and gastric adenocarcinoma. Patients infected with H. pylori carry a 3-6-fold increased risk of developing cancer compared with uninfected individuals. H. pylori strains expressing the cytotoxin-associated antigen A (CagA) are more frequently associated with the development of neoplasia than cagA-negative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Helicobacter pylori-related gastroenterology studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10747974
DOI: 10.1074/jbc.m000959200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Helicobacter pylori Activates Mitogen-activated Protein Kinase Cascades and Induces Expression of the Proto-oncogenes c-fos and c-junPMID 10747974Read ↗

Helicobacter pylori Infection Introduces DNA Double-Strand Breaks in Host CellsSemantic proximity Read ↗

Transactivation of the epidermal growth factor receptor by cag+ Helicobacter pylori induces upregulation of the early growth response gene Egr-1 in gastric epithelial cellsSemantic proximity Read ↗

Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cellsSemantic proximity Read ↗

<i>Helicobacter pylori</i>stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factorsSemantic proximity Read ↗

Helicobacter pylori cytotoxin-associated gene A protein upregulates α-enolase expression via Src/MEK/ERK pathway: Implication for progression of gastric cancerSemantic proximity Read ↗

Helicobacter pylori Induces Antiapoptosis through Nuclear Factor–κB ActivationSemantic proximity Read ↗

Helicobacter pyloriInduces IκB Kinase α Nuclear Translocation and Chemokine Production in Gastric Epithelial CellsSemantic proximity Read ↗

Helicobacter pylori Encoding the Pathogenicity Island Activates Matrix Metalloproteinase 1 in Gastric Epithelial Cells via JNK and ERKSemantic proximity Read ↗

Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.Semantic proximity Read ↗

Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells.Semantic proximity Read ↗

p120 and Kaiso RegulateHelicobacter pylori-induced Expression of Matrix Metalloproteinase-7Semantic proximity Read ↗

Screening of gene expression profiles in gastric epithelial cells induced by <i>Helicobacter pylori</i> using microarray analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.