Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.

Cellular microbiology - 1 Nov 2006

Chang Ya-Jen, Wu Ming-Shiang, Lin Jaw-Town, Pestell Richard G, Blaser Martin J, Chen Ching-Chow

Abstract excerpt

Particular Helicobacter pylori genotypes differentially induce epithelial cell proliferation, but the mechanisms are not characterized. We explored the effect of H. pylori CagA on expression of cyclin D1, an important cell cycle regulator. H. pylori-induced cell survival and cyclin D1 expression were attenuated in a cagA mutant. AP1 and cAMP response element (CRE), but not NF-kappaB, were involved in the induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Cyclin D1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flavonoids

Share to Helicobacter Infections

Share to Imidazoles

Share to Luciferases

Share to Pyridines

Share to Transcription Factor AP-1

Source

Identifiers

PMID: 16759223
DOI: 10.1111/j.1462-5822.2006.00743.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.PMID 16759223Read ↗

Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathwaysSemantic proximity Read ↗

Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathwaysSemantic proximity Read ↗

CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesisSemantic proximity Read ↗

Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cellsSemantic proximity Read ↗

The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric CancerSemantic proximity Read ↗

Functional antagonism between <i>Helicobacter pylori</i> CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cellsSemantic proximity Read ↗

Helicobacter pylori Induces Antiapoptosis through Nuclear Factor–κB ActivationSemantic proximity Read ↗

The <i>Helicobacter pylori</i>'s protein VacA has direct effects on the regulation of cell cycle and apoptosis in gastric epithelial cellsSemantic proximity Read ↗

<i>Helicobacter pylori</i>stimulates host cyclooxygenase-2 gene transcription: critical importance of MEK/ERK-dependent activation of USF1/-2 and CREB transcription factorsSemantic proximity Read ↗

Effect of Helicobacter pylori cdrA on interleukin-8 secretions and nuclear factor kappa B activation.Semantic proximity Read ↗

Helicobacter pylori pathogen inhibits cellular responses to oncogenic stress and apoptosisSemantic proximity Read ↗

IV.Helicobacter pyloristrain-specific activation of signal transduction cascades related to gastric inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.