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Article

Aldose reductase genotypes and cardiorenal complications: an 8-year prospective analysis of 1,074 type 2 diabetic patients.

Diabetes care - 1 Nov 2008

So Wing-Yee, Wang Ying, Ng Maggie C Y, Yang Xilin, Ma Ronald C W, Lam Vincent, Kong Alice P S, Tong Peter C Y, Chan Juliana C N

Abstract excerpt

OBJECTIVE: We report the independent risk association of type 2 diabetic nephropathy with the z-2 allele of the 5'-(CA)(n) microsatellite and C-106T promoter polymorphisms of the aldose reductase gene (ALR2) using a case-control design. In this expanded cohort, we examined their predictive roles on new onset of cardiorenal complications using a prospective design. RESEARCH DESIGN AND METHODS: In this 8-year...

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Identifiers

PMID: 18716049
DOI: 10.2337/dc08-0712
PMCID: PMC2571065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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