Article
[Deletion of chromosome 10q--a marker for metastasis of head-neck carcinomas?].
Laryngo- rhino- otologie - 1 Feb 2000
Bockmühl U, Schmidt S, Petersen S, Petersen I
Abstract excerpt
BACKGROUND: Comparative genomic hybridization (CGH) was applied to squamous cell carcinomas of the head and neck to define genetic alterations that are associated with the metastatic phenotype. METHODS: CGH is a molecular cytogenetic method allowing the comprehensive analysis of a tumor genome for chromosomal imbalances. In total, 23 primary squamous cell carcinomas without evidence of metastasis formation and 20...
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