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Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma

8 Nov 2001

Abstract excerpt

Comparative genomic hybridization (CGH) was used to detect chromosomal changes during metastasis formation of head and neck squamous cell carcinomas (HNSCCs). In total, 92 tumors of 54 patients were investigated. In 34 of these, the metastases were compared to the corresponding primary tumors. The group of metastatic tumors was also compared with 20 nonmetastatic tumors. Gain of 3q was the earliest genetic marker...

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PMID: 11746985
DOI: 10.1002/gcc.1209

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