Article
Identification of a human recent thymic emigrant phenotype.
Proceedings of the National Academy of Sciences of the United States of America - 11 Apr 2000
McFarland R D, Douek D C, Koup R A, Picker L J
Abstract excerpt
The ability to measure human thymic output would be an invaluable tool for the study of the development of the naive T cell repertoire, as well as naive T cell regeneration after intensive cytotoxic chemotherapy or effective antiretroviral therapy of progressive HIV infection. We and others have demonstrated previously that quantification of T cell receptor rearrangement excision circles (TREC) within peripheral...
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