Article
Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration.
Respiratory research - 22 Dec 2015
Blum Walter, Pecze László, Felley-Bosco Emanuela, Schwaller Beat
Abstract excerpt
BACKGROUND: The Ca(2+)-binding protein calretinin is currently used as a positive marker for identifying epithelioid malignant mesothelioma (MM) and reactive mesothelium, but calretinin's likely role in mesotheliomagenesis remains unclear. Calretinin protects immortalized mesothelial cells in vitro from asbestos-induced cytotoxicity and thus might be implicated in mesothelioma formation. To further investigate...
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