Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of CTLA-4 with systemic sclerosis in Japanese patients.

Clinical and experimental rheumatology - 1 Jan 2000

Takeuchi F, Kawasugi K, Nabeta H, Mori M, Tanimoto K

Abstract excerpt

OBJECTIVE: The contribution of CTLA-4 alleles to the pathogenesis of systemic sclerosis (SSc) was studied in Japanese patients. METHODS: CTLA-4 typing in 2 dimorphic sites, +49 A/G and -308 C/T, was carried out in 62 SSc patients and 107 normal subjects by the PCR-RFLP (restriction fragment length polymorphism) method. HLA-DRB1*15 and *08 genotyping were carried out by the PCR-SSCP (simple-stranded DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abatacept
Share to Antigens, Differentiation
Share to CTLA-4 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Immunoconjugates

Share to Pulmonary Fibrosis

Share to Scleroderma, Systemic

Source

Identifiers

PMID: 12508774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CTLA-4 with systemic sclerosis in Japanese patients.PMID 12508774Read ↗

Association of the TNFa13 microsatellite with systemic sclerosis in Japanese patients.Semantic proximity Read ↗

Exon-1 polymorphism of ctla-4 gene is not associated with systemic sclerosis in Iranian patients.Semantic proximity Read ↗

CTLA-4 polymorphisms in Thai patients with rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.Semantic proximity Read ↗

Association of TAP1 and TAP2 with systemic sclerosis in Japanese.Semantic proximity Read ↗

Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01.Semantic proximity Read ↗

Association of CTLA-4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population.Semantic proximity Read ↗

Association of -318 C/T and +49 A/G cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms with a clinical subset of Italian patients with systemic sclerosis.Semantic proximity Read ↗

[The influence of STAT4 rs7574865 (G/T) polymorphism on the risk of clinical and immunological phenotypes of systemic sclerosis in a Russian patient population: Results of a pilot study].Semantic proximity Read ↗

The CTLA-4 and MCP-1 polymorphisms and susceptibility to systemic sclerosis: a meta-analysis.Semantic proximity Read ↗

<i>STAT4</i> is a Genetic Risk Factor for Systemic Sclerosis in a Chinese PopulationSemantic proximity Read ↗

Association study of a polymorphism of the CTGF gene and susceptibility to systemic sclerosis in the Japanese population.Semantic proximity Read ↗

Association of HLA-DQB1*0501 with Scleroderma and its Clinical Features in Chinese PopulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.