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Article

Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils.

Journal of biochemistry - 1 Mar 2000

Takahashi-Yanaga F, Morimoto S, Ohtsuki I

Abstract excerpt

In order to determine the functional consequences of the Arg145Gly mutation in troponin I found in familial hypertrophic cardiomyopathy, human cardiac troponin I and its mutant were expressed in Escherichia coli and purified, and then their effects on the ATPase activity of porcine cardiac myofibrillar preparations from which both troponins C and I had been depleted were examined. Both the wild-type and mutant...

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Identifiers

PMID: 10731705
DOI: 10.1093/oxfordjournals.jbchem.a022615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils.PMID 10731705Read ↗

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