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Article

A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.

The Journal of biological chemistry - 10 Jul 2009

Pinto Jose Renato, Parvatiyar Michelle S, Jones Michelle A, Liang Jingsheng, Ackerman Michael J, Potter James D

Abstract excerpt

Recently four new hypertrophic cardiomyopathy mutations in cardiac troponin C (cTnC) (A8V, C84Y, E134D, and D145E) were reported, and their effects on the Ca(2+) sensitivity of force development were evaluated (Landstrom, A. P., Parvatiyar, M. S., Pinto, J. R., Marquardt, M. L., Bos, J. M., Tester, D. J., Ommen, S. R., Potter, J. D., and Ackerman, M. J. (2008) J. Mol. Cell. Cardiol. 45, 281-288). We performed...

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Identifiers

PMID: 19439414
DOI: 10.1074/jbc.M109.007021
PMCID: PMC2707221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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