Article
[Calcium regulation by troponin and its genetic disorder in striated muscle contraction].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica - 1 Nov 2002
Ohtsuki Iwao
Abstract excerpt
Contraction of skeletal and cardiac muscles is regulated by Ca2+ through specific Ca(2+)-regulatory proteins, troponin and tropomyosin, located in the thin filament. Troponin is a Ca2+ receptive protein consisting of three differet components, troponins C, I, and T. The essential mechanisms of Ca(2+)-regulation are the inhibition of contractile interaction between myosin and actin by the inhibitory action of...
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