Article
Rapid identification of the ABO genotypes by their single-stand conformation polymorphism.
Electrophoresis - 1 Feb 2000
Tsai L C, Kao L G, Chang J G, Lee H H, Linacre A, Lee J C
Abstract excerpt
The ABO locus on chromosome 9 contains many more alleles than are currently used routinely in forensic science. The use of single-strand conformation polymorphism (SSCP) can separate sequence polymorphisms that differ by only one base. The SSCP process used allows for both single- and double-stranded polymerase chain reaction (PCR) products to be visualized. The six ABO genotypes can be differentiated by the...
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