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Article

Detection of ABO blood group polymorphism by denaturing gradient gel electrophoresis.

Human molecular genetics - 1 Aug 1992

Johnson P H, Hopkinson D A

Abstract excerpt

We report the use of a polymerase chain reaction (PCR) format together with denaturing gradient gel electrophoresis (DGGE) which allows rapid identification of the 6 major genotypes (AA, AO, BB, BO, AB and OO) of the human ABO blood group polymorphism in a single amplification. The procedure also distinguishes hitherto undescribed polymorphisms associated with the O and B alleles. Thus in testing 95 unrelated...

Topics

ABO Blood-Group System
Alleles
Base Sequence
DNA
Electrophoresis
Genotype
Heterozygote
Homozygote
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1303212
DOI: 10.1093/hmg/1.5.341

Genes

ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1303212-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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