Article
Frequency and allelic association of common variants in the lipoprotein lipase gene in different ethnic groups: the Wandsworth Heart and Stroke Study.
Genetic epidemiology - 1 Mar 2000
Hall S, Talmud P J, Cook D G, Wicks P D, Rothwell M J, Strazzullo P, Sagnella G A, Cappuccio F P
Abstract excerpt
The lower serum triglyceride (Tg), higher high density cholesterol (HDL-C) levels and low coronary heart disease (CHD) mortality in black populations, contrast with that in whites. By comparison, South Asian populations display a higher mortality from CHD associated with increased Tg and low HDL-C levels. Lipoprotein lipase (LPL) plays a major role in Tg metabolism. To determine if variation in the LPL gene...
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