Article
Common variants in the lipoprotein lipase gene in Brazil: association with lipids and angiographically assessed coronary atherosclerosis.
Clinical chemistry and laboratory medicine - 1 Oct 2003
Rios Domingos L S, Vargas André F, Ewald Gisele M, Torres Marco R, Zago Alcides J, Callegari-Jacques Sídia M, Hutz Mara H
Abstract excerpt
Lipoprotein lipase is the rate-limiting enzyme in the lipolysis of plasma triglyceride-rich lipoproteins. We studied six variants (T-93G, D9N, N291S, PvuII, HindIII and S447X) in the lipoprotein lipase (LPL) gene in 309 non-diabetic patients with angiographically assessed coronary artery disease and in 197 controls in a southern Brazilian population of European descent. The HindIII H-allele was associated with...
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