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Article

Sequence, expression and functional analysis of the Coccidioides immitis ODC (ornithine decarboxylase) gene.

Gene - 25 Jan 2000

Guevara-Olvera L, Hung C Y, Yu J J, Cole G T

Abstract excerpt

The ornithine decarboxylase (ODC) gene of the human respiratory fungal pathogen, Coccidioides immitis (Ci) was cloned, sequenced, chromosome-mapped, and expressed in Escherichia coli (Ec). The genomic, cDNA and translated sequences are presented. Transformation of an ODC null mutant strain of Ec (EWH 319) with the Ci ODC gene was conducted to confirm function of the protein encoded by the fungal gene. Activity of...

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PMID: 10721738
DOI: 10.1016/s0378-1119(99)00496-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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