Article
Receptor recognition by a hepatitis B virus reveals a novel mode of high affinity virus-receptor interaction.
The EMBO journal - 15 Mar 2000
Urban S, Schwarz C, Marx U C, Zentgraf H, Schaller H, Multhaup G
Abstract excerpt
The duck hepatitis B virus model system was used to elucidate the characteristics of receptor (carboxypeptidase D, gp180) interaction with polypeptides representing the receptor binding site in the preS part of the large viral surface protein. We demonstrate the pivotal role of carboxypeptidase D for virus entry and show its C-domain represents the virus attachment site, which binds preS with extraordinary...
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