Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural Analysis of the Mechanism of Adenovirus Binding to Its Human Cellular Receptor, CAR

19 Nov 1999

Abstract excerpt

Binding of virus particles to specific host cell surface receptors is known to be an obligatory step in infection even though the molecular basis for these interactions is not well characterized. The crystal structure of the adenovirus fiber knob domain in complex with domain I of its human cellular receptor, coxsackie and adenovirus receptor (CAR), is presented here. Surface-exposed loops on knob contact one...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10567268
DOI: 10.1126/science.286.5444.1579

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural Analysis of the Mechanism of Adenovirus Binding to Its Human Cellular Receptor, CARPMID 10567268Read ↗

Human adenovirus binding to host cell receptors: a structural viewSemantic proximity Read ↗

Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor.Semantic proximity Read ↗

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactionsSemantic proximity Read ↗

Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor.Semantic proximity Read ↗

Identification of a Conserved Receptor-Binding Site on the Fiber Proteins of CAR-Recognizing AdenoviridaeSemantic proximity Read ↗

Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.Semantic proximity Read ↗

Insights into adenovirus host cell interactions from structural studiesSemantic proximity Read ↗

Identification of chicken CAR homology as a cellular receptor for the emerging highly pathogenic fowl adenovirus 4 via unique binding mechanismSemantic proximity Read ↗

Selection Pressure in the Human Adenovirus Fiber Knob Drives Cell Specificity in Epidemic Keratoconjunctivitis.Semantic proximity Read ↗

The coxsackievirus and adenovirus receptor: virological and biological beautySemantic proximity Read ↗

Conserved Fiber-Penton Base Interaction Revealed by Nearly Atomic Resolution Cryo-Electron Microscopy of the Structure of Adenovirus Provides Insight into Receptor InteractionSemantic proximity Read ↗

Unity and diversity in the human adenoviruses: exploiting alternative entry pathways for gene therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.