Article
Regulatory polymorphisms in the IL-10 gene promoter and HBV-related acute liver failure in the Chinese population.
Journal of viral hepatitis - 1 Nov 2009
Yan Z, Tan W, Zhao W, Dan Y, Wang X, Mao Q, Wang Y, Deng G
Abstract excerpt
Recent reports indicated that high levels of interleukin 10 (IL-10) contribute to the monocytes paralysis and poor clinical outcome in acute liver failure (ALF). Polymorphisms in the promoter region of IL-10 affect IL-10 production and confer susceptibility to inflammatory diseases. The aim of this study was to determine the possible association of the three polymorphisms (A-1082G, T-819C, A-592C) in the IL-10...
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