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Article

Expression and functional analysis of Uch-L3 during mouse development.

Molecular and cellular biology - 1 Apr 2000

Kurihara L J, Semenova E, Levorse J M, Tilghman S M

Abstract excerpt

Mice homozygous for the s(1Acrg) deletion at the Ednrb locus arrest at embryonic day 8.5. To determine the molecular basis of this defect, we initiated positional cloning of the s(1Acrg) minimal region. The mouse Uch-L3 (ubiquitin C-terminal hydrolase L3) gene was mapped within the s(1Acrg) minimal region. Because Uch-L3 transcripts were present in embryonic structures relevant to the s(1Acrg) phenotype, we...

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Identifiers

PMID: 10713173
DOI: 10.1128/MCB.20.7.2498-2504.2000
PMCID: PMC85452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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