Article
Porcine UCHL1: genomic organization, chromosome localization and expression analysis.
Molecular biology reports - 1 Feb 2012
Larsen Knud, Madsen Lone Bruhn, Bendixen Christian
Abstract excerpt
The human UCHL1 gene encodes the ubiquitin C-terminal hydrolase UCHL1, which comprises more than 2% of total brain protein. UCHL1 is a component of the ubiquitin-proteasome system, which degrades overexpressed and damaged proteins. Mutations in the UCHL1 gene are associated with susceptibility to and protection from Parkinson's disease. Here we report cloning, characterization, expression analysis and mapping of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
