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Article

Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa.

Molecular and cellular biology - 1 Apr 2000

Schreiber J, Riethmacher-Sonnenberg E, Riethmacher D, Tuerk E E, Enderich J, Bösl M R, Wegner M

Abstract excerpt

The GCM family of transcription factors consists of Drosophila melanogaster GCM, an important regulator of gliogenesis in the fly, and its two mammalian homologs, GCMa and GCMb. To clarify the function of these mammalian homologs, we deleted GCMa in mice. Genetic ablation of murine GCMa (mGCMa) is embryonic lethal, with mice dying between 9.5 and 10 days postcoitum. At the time of death, no abnormalities were...

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Identifiers

PMID: 10713170
DOI: 10.1128/MCB.20.7.2466-2474.2000
PMCID: PMC85439

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Source receipt: pubmed, retrieved 7 Sept 2026.

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