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Article

Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2000

Yuan B, Li C, Kimura S, Engelhardt R T, Smith B R, Minoo P

Abstract excerpt

In vitro and in vivo results are consistent with a critical role for NKX2.1, an epithelial homeodomain transcription factor in lung morphogenesis. Nkx2.1 null mutant embryos die at birth due to respiratory insufficiency caused by profoundly abnormal lungs. However, the precise role of NKX2.1 in t...

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PMID: 10706142
DOI: 10.1002/(SICI)1097-0177(200002)217:2<180::AID-DVDY5>3.0.CO;2-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10706142-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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