Article
The Drosophila gene abstrakt, required for visual system development, encodes a putative RNA helicase of the DEAD box protein family.
Mechanisms of development - 1 Mar 2000
Schmucker D, Vorbrüggen G, Yeghiayan P, Fan H Q, Jäckle H, Gaul U
Abstract excerpt
The molecular mechanisms underlying axonal pathfinding are not well understood. In a genetic screen for mutations affecting the projection of the larval optic nerve we isolated the abstrakt locus. abstrakt is required for pathfinding of the larval optic nerve, and it also affects development in both the adult visual system and the embryonic CNS. Here we report the molecular characterization of abstrakt. It...
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