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Article

Regulation of Notch Signaling by an Evolutionary Conserved DEAD Box RNA Helicase, Maheshvara in Drosophila melanogaster.

Genetics - 1 Nov 2015

Surabhi Satya, Tripathi Bipin K, Maurya Bhawana, Bhaskar Pradeep K, Mukherjee Ashim, Mutsuddi Mousumi

Abstract excerpt

Notch signaling is an evolutionary conserved process that influences cell fate determination, cell proliferation, and cell death in a context-dependent manner. Notch signaling is fine-tuned at multiple levels and misregulation of Notch has been implicated in a variety of human diseases. We have characterized maheshvara (mahe), a novel gene in Drosophila melanogaster that encodes a putative DEAD box protein that...

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Identifiers

PMID: 26400611
DOI: 10.1534/genetics.115.181214
PMCID: PMC4649636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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