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Article

p53 mutation pattern in hepatocellular carcinoma in workers exposed to vinyl chloride.

Cancer - 1 Mar 2000

Weihrauch M, Lehnert G, Köckerling F, Wittekind C, Tannapfel A

Abstract excerpt

BACKGROUND: Vinyl chloride (VC) is a known animal and human carcinogen that is associated with liver angiosarcoma and most likely also with hepatocellular carcinoma (HCC) in humans. METHODS: The authors examined the presence of p53 gene mutations in 18 HCC specimens from patients with known exposure to VC (median, 8883 parts per million-years; median duration, 245 months). In all cases, other risk factors for the...

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PMID: 10699891

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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