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Article

Imprinted genes as potential genetic and epigenetic toxicologic targets.

1 Mar 2000

Abstract excerpt

Genomic imprinting is an epigenetic phenomenon in eutherian mammals that results in the differential expression of the paternally and maternally inherited alleles of a gene. Imprinted genes are necessary for normal mammalian development. This requirement has been proposed to have evolved because of an interparental genetic battle for the utilization of maternal resources during gestation and postnatally. The...

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Share to Epigenetics and DNA Methylation
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PMID: 10698719
DOI: 10.1289/ehp.00108s15

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