Polymorphisms, genomic imprinting and cancer susceptibility.

doi:10.1016/s1383-5742(98)00018-0

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Article

Polymorphisms, genomic imprinting and cancer susceptibility.

Mutation research - 1 Jan 1999

Pulford D J, Falls J G, Killian J K, Jirtle R L

Abstract excerpt

Polymorphisms have been identified in proto-oncogenes and tumor suppressor genes that predispose people to cancer. Recent evidence indicates that genomic imprinting, an epigenetic form of gene regulation that results in uniparental gene expression, can also function as a cancer predisposing event...

Topics

Genes, Tumor Suppressor
Genetic Predisposition to Disease
Genomic Imprinting
Humans
Neoplasms
Polymorphism, Genetic
Proto-Oncogenes

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