Polymorphisms, genomic imprinting and cancer susceptibility.

Abstract excerpt

Polymorphisms have been identified in proto-oncogenes and tumor suppressor genes that predispose people to cancer. Recent evidence indicates that genomic imprinting, an epigenetic form of gene regulation that results in uniparental gene expression, can also function as a cancer predisposing event. Thus, cancer susceptibility is increased by both Mendelian inherited genetic and non-Mendelian inherited epigenetic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genes, Tumor Suppressor
• Share to Genetic Predisposition to Disease
• Share to Genomic Imprinting