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Article

Highly related immunoglobulin light chain sequences in different multiple sclerosis patients.

Journal of neuroimmunology - 1 Dec 1999

Blalock J E, Zhou S R, Maier C C, Galin F S, Whitaker J N

Abstract excerpt

Although immunoglobulin G and free light (L) chains of oligoclonal origin in cerebrospinal fluid (CSF) are the most common immunologic abnormalities in multiple sclerosis (MS), it is unknown whether homologous CSF L chain sequences are present in different individuals with MS. Using Southern blotting, a particular kappa (kappa) L chain variable region (V) probe was recently found to hybridize to Vkappa cDNA from...

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Share to Amino Acid Sequence
Share to B-Lymphocytes
Share to Immunoglobulin Light Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Variable Region

Share to Multiple Sclerosis

Share to Myelin Basic Protein

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 10695719
DOI: 10.1016/s0165-5728(99)00188-5

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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