Article
Immunogenetic correlates of susceptibility to infection with Heligmosomoides polygyrus in outbred mice.
Parasitology - 1 Aug 1990
Keymer A E, Tarlton A B, Hiorns R W, Lawrence C E, Pritchard D I
Abstract excerpt
Outbred MF1 mice were characterized with respect to their susceptibility to infection with Heligmosomoides polygyrus (Nematoda) on the basis of faecal egg counts after 8 weeks of repeated infection (50 larvae/week). Selective breeding for resistance and susceptibility was carried out over 3 generations. The H-2 type of a sample of the mice was determined, and antigen recognition assessed on the basis of Western...
Topics
- Animals
- Blotting, Western
- Breeding
- Disease Susceptibility
- Feces
- Female
- Genes, MHC Class I
- Genotype
- Haplotypes
- Histocompatibility Antigens
- Male
- Mice