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Article

Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2001

Bikoff E K, Wutz G, Kenty G A, Koonce C H, Robertson E J

Abstract excerpt

Current ideas about DM actions have been strongly influenced by studies of mutant strains expressing the H-2(b) haplotype. To evaluate DM contributions to class II activities in BALB/c mice, we generated a novel mutation at the DMa locus via embryonic stem cell technology. Unlike long-lived A(b)/class II-associated invariant chain-derived peptide (CLIP) complexes, mature A(d) and E(d) molecules are loosely...

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Source

Identifiers

PMID: 11290790
DOI: 10.4049/jimmunol.166.8.5087

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SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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