Article
Tumor progression and metastasis.
Carcinogenesis - 1 Mar 2000
Yokota J
Abstract excerpt
It is now widely accepted that cancer is attributed to the accumulation of genetic alterations in cells. Thus, to understand the molecular mechanisms of cancer metastasis, it is indispensable to identify the genes whose alterations accumulate during cancer progression as well as the genes whose expression is responsible for the acquisition of metastatic potential in cancer cells. Molecular analyses of cancer...
Topics
- Animals
- Disease Progression
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Humans
- Mutation
- Neoplasm Metastasis
- Neoplasms
- Oncogenes
- Phenotype
