Article
Mutational drivers of cancer cell migration and invasion.
British journal of cancer - 1 Jan 2021
Novikov Nikita M, Zolotaryova Sofia Y, Gautreau Alexis M, Denisov Evgeny V
Abstract excerpt
Genomic instability and mutations underlie the hallmarks of cancer-genetic alterations determine cancer cell fate by affecting cell proliferation, apoptosis and immune response, and increasing data show that mutations are involved in metastasis, a crucial event in cancer progression and a life-threatening problem in cancer patients. Invasion is the first step in the metastatic cascade, when tumour cells acquire...
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