Article
Tumor metastasis: moving new biological insights into the clinic.
Nature medicine - 1 Nov 2013
Wan Liling, Pantel Klaus, Kang Yibin
Abstract excerpt
As the culprit behind most cancer-related deaths, metastasis is the ultimate challenge in our effort to fight cancer as a life-threatening disease. The explosive growth of metastasis research in the past decade has yielded an unprecedented wealth of information about the tumor-intrinsic and tumor-extrinsic mechanisms that dictate metastatic behaviors, the molecular and cellular basis underlying the distinct...
Topics
- Cell Survival
- Drug Discovery
- Epithelial-Mesenchymal Transition
- Humans
- Models, Biological
- Mutation
- Neoplasm Invasiveness
- Neoplasm Metastasis
- Oncogenes
- Stromal Cells
- Translational Research, Biomedical