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Article

The NS5a gene of hepatitis C virus in patients treated with interferon-alpha.

Journal of medical virology - 1 Apr 2000

McKechnie V M, Mills P R, McCruden E A

Abstract excerpt

Patients infected with hepatitis C virus (HCV) genotype 3 have a better response to interferon-alpha (IFN-alpha) therapy than those infected with genotype 1. There are extensive sequence differences between genotypes in the 3' half of the NS5a gene. An association between IFN-alpha response and the interferon sensitivity-determining region (ISDR) (amino acids 2209-2248) of HCV genotype 1b has been described...

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Share to Alanine Transaminase
Share to Genes, Viral
Share to Hepacivirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferon-alpha

Share to Polymorphism, Single-Stranded Conformational

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Share to Viral Nonstructural Proteins

Source

Identifiers

PMID: 10686018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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