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Article

Sequencing of E2 and NS5A regions of HCV genotype 3a in Brazilian patients with chronic hepatitis.

Memorias do Instituto Oswaldo Cruz - 1 Feb 2010

Malta Fernanda de Mello, Medeiros-Filho José Eymard Moraes de, Azevedo Raymundo Soares de, Gonçalves Luzia, Silva Luiz Caetano da, Carrilho Flair José, Pinho João Renato Rebello

Abstract excerpt

Hepatitis C virus (HCV) is a major cause of liver disease throughout the world. The NS5A and E2 proteins of HCV genotype 1 were reported to inhibit the double-stranded (ds) RNA-dependent protein kinase (PKR), which is involved in the cellular antiviral response induced by interferon (IFN). The response to IFN therapy is quite different between genotypes, with response rates among patients infected with types 2...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 20209336
DOI: 10.1590/s0074-02762010000100014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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