Article
Variations of hepatitis C virus NS5B sequence (nucleotides 8261-8566) do not correlate with response to interferon-alpha therapy.
Journal of viral hepatitis - 1 Jan 1995
Nelson D R, Gray A H, Kolberg J A, Joh J, Urdea M S, Mizokami M, Davis G L, Lau J Y
Abstract excerpt
Hepatitis C virus (HCV) is an RNA virus with the NS5B gene encoding an RNA-dependent RNA polymerase. Interferon-alpha (IFN-alpha) is effective against HCV and its effect is believed to be related to its antiviral activity. To determine whether sequence variations of the HCV NS5B region correlate...
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