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Article

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin.

The Journal of cell biology - 21 Feb 2000

Li D, Mrsny R J

Abstract excerpt

Occludin is an integral membrane protein of the epithelial cell tight junction (TJ). Its potential role in coordinating structural and functional events of TJ formation has been suggested recently. Using a rat salivary gland epithelial cell line (Pa-4) as a model system, we have demonstrated that...

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Source

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Identifiers

PMID: 10684259
DOI: 10.1083/jcb.148.4.791
PMCID: PMC2169369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10684259-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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