Article
Completion of meiosis in Drosophila oocytes requires transcriptional control by grauzone, a new zinc finger protein.
Development (Cambridge, England) - 1 Mar 2000
Chen B, Harms E, Chu T, Henrion G, Strickland S
Abstract excerpt
Mutations in grauzone or cortex cause abnormal arrest in Drosophila female meiosis. We cloned grauzone and identified it as a C2H2-type zinc finger transcription factor. The grauzone transcript is present in ovaries and at later developmental stages. A Grauzone-GFP fusion protein is functional and localizes to nuclei of both nurse cells and follicle cells during oogenesis. Three lines of evidence indicate that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
