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Article

Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.

The American journal of clinical nutrition - 1 Aug 2008

Orton Sarah-Michelle, Morris Andrew P, Herrera Blanca M, Ramagopalan Sreeram V, Lincoln Matthew R, Chao Michael J, Vieth Reinhold, Sadovnick A Dessa, Ebers George C

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) risk is determined by both genes and environment. One of the most striking features of MS is its geographic distribution, particularly the pattern of high MS frequency in areas with low sunlight exposure, the main inducer of vitamin D synthesis. Recent epidemiologic, experimental, and clinical evidence support an effect for low environmental supplies of vitamin D in mediating...

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Calcitriol

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Source

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Identifiers

PMID: 18689381
DOI: 10.1093/ajcn/88.2.441
PMCID: PMC2740974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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