Genetic polymorphisms related to vitamin D and the therapeutic potential of vitamin D in multiple sclerosis.

Abstract excerpt

Vitamin D receptors (VDRs), which are responsible for most vitamin D functions, are expressed on various immune cells. Vitamin D is considered to be a potent immunomodulator. A variety of cells in the central nervous system (CNS) also express VDRs; thus, vitamin D may play a role in the regulation of neurodegeneration and repair processes within the CNS. Considered together with epidemiological studies, low...

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• Genetic Predisposition to Disease
• Multiple Sclerosis
• Polymorphism, Genetic
• Receptors, Calcitriol
• Vitamin D