Article
Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2015
Laursen Julie H, Søndergaard Helle Bach, Albrechtsen Anders, Frikke-Schmidt Ruth, Koch-Henriksen Nils, Soelberg Sørensen Per, Sellebjerg Finn, Oturai Annette
Abstract excerpt
BACKGROUND: Evidence is accumulating supporting a beneficial effect of vitamin D in multiple sclerosis (MS). Genome-wide association studies (GWAS) have shown significant associations between 25-hydroxyvitamin D (25(OH)D) and single nucleotide polymorphisms (SNPs) in key genes in the vitamin D metabolism. OBJECTIVE: To examine the association between 25(OH)D and six GWAS SNPs and environmental factors in 1497 MS...
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