Article
CYP27A1, CYP24A1, and RXR-α Polymorphisms, Vitamin D, and Multiple Sclerosis: a Pilot Study.
Journal of molecular neuroscience : MN - 1 Sept 2018
Agnello Luisa, Scazzone Concetta, Lo Sasso Bruna, Ragonese Paolo, Milano Salvatore, Salemi Giuseppe, Ciaccio Marcello
Abstract excerpt
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease resulting from a complex interaction of genetic and environmental factors. Hypovitaminosis D seems to contribute to MS susceptibility as both an environmental and a genetic risk factor. The aim of our study was to investigate the association of SNPs in CYP27A1, CYP24A1, and RXR- α genes, vitamin D status, and MS risk. We performed a nested...
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