Article
Estimation of variance components of quantitative traits in inbred populations.
American journal of human genetics - 1 Feb 2000
Abney M, McPeek M S, Ober C
Abstract excerpt
Use of variance-component estimation for mapping of quantitative-trait loci in humans is a subject of great current interest. When only trait values, not genotypic information, are considered, variance-component estimation can also be used to estimate heritability of a quantitative trait. Inbred pedigrees present special challenges for variance-component estimation. First, there are more variance components to be...
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